Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans

Wanqing Liu; Quentin M Anstee; Xiaoliang Wang; Samer Gawrieh; Eric R. Gamazon; Shaminie Athinarayanan; Yang-Lin Liu; Rebecca Darlay; Heather J Cordell; Ann K Daly; Chris P Day; Naga Chalasani

doi:doi:10.18632/aging.101067

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Research Paper Volume 9, Issue 1 pp 26—40

Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans

Figure 1. Cis-eQTL mapping for PNPLA3 in human livers. Shown here were both statistical significance (-log₁₀^p) (left y-axis) and recombination rate (right y-axis) across the PNPLA3 locus ±1Mb region on Chromosome 22 and centered to rs139051 (A) and a zoomed region centered to the PNPLA3 gene region (B).