Research Paper Volume 8, Issue 10 pp 2551—2567

Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria

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Figure 2. DR improves learning and spatial memory. (A) Learning behaviour measured as time to find the target hole in a Barnes maze during the training period (day 1 to 4). DR (red, n=12, 33 months), AL (black, n=5, 30 months) and young mice (green, n=7, 10 months,). Statistical significance between groups was tested by One way ANOVA for each day separately. (*P<0.05) (B) Short term (short) and long term (long) memory expressed as the time to find the target hole. Young mice n=7, AL, n=5, DR, n=12, One way ANOVA, *p<0.05. (C) Short- and long term memory expressed as hole scores for head poking from the same mice as in A and B.