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Research Paper Volume 8, Issue 12 pp 3321—3340

RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma

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Figure 4. Gene expression analysis for p65 hyperactivation in diffuse large B-cell lymphoma (DLBCL). (A) Heatmaps for gene differentially expressed between p65high (IHC ≥50%) and p65low (IHC <50%) patients in DLBCL overall and in ABC-DLBCL (false discovery rate <0.30 and <0.20, respectively). (B) Heatmaps for genes differentially expressed between p65high (IHC ≥50%) and p65low (IHC <50%) patients and between p65high (IHC ≥50%) and p65intermediate (IHC 10-40%) patients with germinal center B-cell–like DLBCL (false discovery rate <0.05 and <0.20, respectively).