Figure 9. Activity of SM on estrogen receptor ERα (A) and ERβ (B) -estrogen response element (ERE) luciferases reporter gene expression. Data are the mean ± standard deviation of quadruplicate analyses, expressed relative to that of treatment with 0.1% DMSO. P values are for one-way analysis of variance (ANOVA) comparing treatment groups with untreated mice. ***P < 0.01, **P < 0.01 and *P < 0.05 compared with Con group; ###p < 0.001, compared to SM or 0.01 μM E2.