Research Paper Volume 9, Issue 1 pp 187—208

Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress

Figure 4. Forearm blood flow (FBF) area under the dose-response curve (AUC) in response to acetylcholine (FBFACh) without (-) or with (+) NG monomethyl-L-arginine (L-NMMA; left) and nitric oxide-dependent dilation (right) at week 0 and after 12 weeks of placebo or curcumin supplementation. Data are mean±SE; *P<0.02 vs. corresponding group week FBFACh (left); Group by time P=0.04, *P=0.03 vs. curcumin week 0 (right).