Research Paper Volume 9, Issue 2 pp 353—369

Hypothalamic ΔFosB prevents age-related metabolic decline and functions via SNS

Figure 6. AAV-ΔFosB mice are resistant to age-related adiposity and impairment in glucose metabolism. Mice were stereotaxically injected into VHT with AAV-∆FosB or AAV-GFP and glucose metabolism was assessed 38-40 weeks post-surgically (n=4). (A) Body weight (B) Abdominal epididymal fat pad weight (C) GTT glucose (D) GTT insulin. (E) ITT glucose. Data are expressed as mean ± SEM. *p<0.05, **p<0.01