Research Paper Volume 9, Issue 2 pp 370—380

The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy

Figure 1. Circulating MNCs of long living individuals (LLIs) show similar BPIFB4 gene levels but modulation in HIF-1α hallmark factors compared to young controls. Box plots of the mRNA levels (log2 scale) of BPIFB4 and HIF-1α-associated factors (CXCR4, ALDO-C, ADM, miR-210, VEGF-A, GLUT-1, AK3) in LLIs (N=45) versus controls (N=63).