Figure 6. Aging and reproduction associated with metabolic variations in C. elegans. (A) PCA included young adults and 10-day adults WT, glp-1 and daf-16;glp-1. PC1 and PC2 stand for the first and second principal components, respectively. (B) Model on how germline less signals regulate metabolome of worms to attenuate aging. See detailed explanation in the main text of the discussion.