Research Paper Volume 9, Issue 3 pp 706—740

Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

Figure 5. LSI-based natural language investigation of the core 30 GIT2KO PTL-associated transcripts. The noun-phrase wordcloud for the 30 core PTL-associated coherently regulated transcripts was generated using the collective processing module of Textrous! coupled to proportional text representation output with Wordle. Noun-phrase frequency score analysis (histogram on left of panel A) of the resultant wordcloud was performed using WriteWords text analysis (A). In addition to LSI-based interpretation of the core 30 PTL-associated coherently regulated transcripts and orthogonal analysis was performed using Genes2wordcloud (Mammalian Phenotype annotation database: B). The wordcloud output in panel B is from Genes2wordcloud as is the associated histogram displaying the top 20 word frequencies from the cloud. For both wordclouds in panels A and B, the text size is directly proportional to the word/phrase frequency generated from either Textrous! or Genes2wordcloud.