Research Paper Volume 9, Issue 3 pp 753—768

Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age

Figure 2. Four DDO promoter CpG sites associated with human age in white blood cells from 2316 samples sourced from the MARMAL-AID methylation repository. Each association is fitted with an overall loess regression model, with the regression statistics shown in the top right of each panel. Points are coloured and shaped to represent both males (black, circles) and females (grey, triangles) separately.