Research Paper Volume 9, Issue 3 pp 823—851

Amyotrophic lateral sclerosis, gene deregulation in the anterior horn of the spinal cord and frontal cortex area 8: implications in frontotemporal lobar degeneration

Figure 6. Gel electrophoresis and western blotting to glutamate receptor ionotropic, NMDA 2A (NMDAR2A), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor 1 (GluR-1), glutamate decarboxylase 1 (GAD1) and gamma-aminobutyric acid receptor subunit beta-2 (GABAAB2) in the frontal cortex area 8 of control and ALS. Significant increased levels of GluR-1 and a tendency to increased levels of GABAAB2 are seen in ALS when compared with controls. The significance level is set at ** p < 0.01 and tendencies at # < 0.1.