Research Paper Volume 9, Issue 3 pp 932—954

MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2

Figure 4. Deregulation of miR-34a-3p alters apoptosis and necrosis of meningioma cells. Ben-Men-1 cells were transfected either with miR-34a-3p (mimic) and scrambled control (A) or anti-miR-34a-3p (inhibitor) and scrambled control (B). Cells were harvested 48 h and 72 h after transfection, stained with Annexin V / PI and analyzed by FACS. Values are means ± SEM of three independent experiments (*, P < 0.05).