Research Paper Volume 9, Issue 3 pp 999—1011

Long non-coding RNA LOC100129148 functions as an oncogene in human nasopharyngeal carcinoma by targeting miR-539-5p

Figure 8. LOC100129148's oncogenic activity is in part through negative regulation of miR-539-5p, and then activation of KLF12 in NPC cells. (A) Statistical analysis of trypan blue staining. (B) Protein expression of KLF12 in miR-539-5p, sh-KLF12, LOC100129148, or LOC100129148+sh-KLF12 treated CNE-1 and SUNE-1 cells. Assays were performed in triplicate. *P < 0.05. Means ± SEM are shown. Statistical analysis was conducted using student One-Way ANOVA test.