Research Paper Volume 9, Issue 3 pp 1055—1068

An epigenetic aging clock for dogs and wolves

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Figure 1. Conservation of epigenetic aging. Normalized correlation (z) between age and DNA methylation for CpG sites in one species versus the same correlation computed at syntenic CpG sites in another species. The species comparisons are shown, as follows: (A) Wolves versus Dogs, (B) Human versus Canid (pooled dogs and wolves), (C) Human versus Dogs, and (D) Human versus Wolves.