Research Paper Volume 9, Issue 4 pp 1153—1185

The age- and sex-specific decline of the 20s proteasome and the Nrf2/CncC signal transduction pathway in adaption and resistance to oxidative stress in Drosophila melanogaster

Figure 1. Hydrogen peroxide resistance declines with age. (A-D) Males and females of the Actin-GS-255B strain crossed to the w[1118] strain were aged to 3 days or 60 days and then transferred to vials containing kimwipes soaked in 1.0M to 8.0M H2O2 dissolved in 5% sucrose solution, and flies were scored as dead when completely immobile, as described previously [43]. (A) 3 day old females. (B) 3 day old males. (C) 60 day old females. (D) 60 day old males.