Research Paper Volume 9, Issue 4 pp 1219—1232

The differential spatiotemporal expression pattern of shelterin genes throughout lifespan

Figure 2. TRF2 is highly and ubiquitously expressed during embryonic development up to E16 and persists afterwards specifically in the brain. Representative photomicrographs of TRF2 immunostaining on sections of mouse embryos (3,3' diaminobenzidine (DAB) substrate, brown, hematoxylin counterstaining) at different stages before birth. B: brain, H: heart, L: liver, K: kidney. Unless otherwise indicated, scale bars represent 50µm.