Research Paper Volume 9, Issue 4 pp 1307—1325

Paradoxical aging in HIV: immune senescence of B Cells is most prominent in young age

Figure 5. B Cells of young HIV exhibit markers of Immune activation and exhaustion. (A) Example of gating strategy for CD80+, PDL1+ and FcRL4+ B cells. (B) Frequencies of CD80+ B cell and (C) Frequencies of PDL1+ B cell in HC (Grey) and HIV (Black). Age groups are depicted as squares (young, <40 years) and circles (old, ≥60 years). *, Statistical significance at p <0.05 by Mann-Whitney test.