Research Paper Volume 9, Issue 4 pp 1307—1325

Paradoxical aging in HIV: immune senescence of B Cells is most prominent in young age

Figure 6. Plasmablasts at T0 are positively correlated with B cellular response to H1N1 in HIV (Black) and HC (Grey). Frequencies of plasmablast before vaccination were correlated with the H1N1 specific spontaneous ASC by ELISpot in PBMC at 7 days after vaccination. ELISpot values are expressed as log2 scale. Age groups depicted as squares (young, <40 years), triangles (middle, 40-59 years) and circles (old, ≥60 years). Spearman correlation was performed.