Research Paper Volume 9, Issue 5 pp 1359—1374

Aging-associated oxidative stress inhibits liver progenitor cell activation in mice

Figure 1. Liver injury in old mice with CDE diet. Y/O mice were fed with normal/CDE diet for 3 weeks. (A) Cumulative survival rates of Y/O mice with CDE diet were analyzed (n = 5 mice per group). (B-C) Serum and liver tissues from Y/O mice fed with normal/CDE diet were sampled on day 21. (B) Serum levels of AST and ALT were measured. Results are mean ± SEM from three independent experiments (n = 6 mice per group). (C) Liver tissues were sectioned for histological examination. Scale bar = 100 μm. Representative images from one experiment out of three are shown. *P < 0.05.