Research Paper Volume 9, Issue 5 pp 1404—1413

Diffuse colonies of human skin fibroblasts in relation to cellular senescence and proliferation

Figure 3. Correlation analysis. (A) Representative microphotographs of fibroblasts immunofluorescently labeled for Ki67. (Ki67+ cells are marked with arrows), (B) The fraction of Ki67+ cells in mass culture vs. four indicated clonogenic endpoints; all correlations, except for a correlation with the dense colony fraction (p=0.07), were statistically significant at p<0.05, (C) The fraction of diffuse colonies (X-axis) vs. the other endpoints (Y-axis, as indicated). (D) The fraction of Ki67+ cells (X-axis) in mass culture and the other endpoints (Y-axis, as indicated). Note: Red color indicate a trend-line with the r value that is not statistically significant (p=0.07). The r values colored in black are statistically significant (p<0.05).