Research Paper Volume 9, Issue 5 pp 1440—1452

Friedreich’s ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency

Figure 1. Generation of iPSC lines from FRDA-patients. Immunostaining of FA6 CL1 (A, D), CL2 (B, E), CL3 (C, F) for OCT4 (A-C) and TRA-1-60 (D-F); FA8 CL1 (G, J), CL2 (H, K), CL3 (I, L) for OCT4 (G-I) and TRA-1-60 (J-L); FA9 CL1 (M, P), CL2 (N, Q), CL3 (O, R) for OCT4 (M-O) and TRA-1-60 (P-R). (S) Negative isotype. Cells were counterstained with DAPI (blue). Scale bars: 50 μm.