Review Volume 9, Issue 6 pp 1477—1536

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

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Figure 11. Effects of berberine on TP53, miRs, apoptosis and drug resistance. Berberine can induce the expression of TP53 and miRs which can alter the expression of many genes involved in the regulation of apoptosis, cell cycle progression and drug resistance. miRs which are oncomirs are indicated in maroon, miRs which are tumor suppressor miRs are indicated in blue.