Research Paper Volume 9, Issue 6 pp 1595—1606

Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

Figure 3. Contractile responses of the mesenteric artery to A: KPSS, B: phenylephrine C: U46619 (U4) and D: angiotensin II (Ang II) in the absence or presence of L-NAME in young and old mice (n=3-6). Contractile responses to Ang II in the absence or presence of tempol, tempol + catalase or indomethacin in E: young mice and F: aged mice (n=3). All data are mean ± S.E.M. *P<0.05 vs young, two-way ANOVA with Tukey’s post-hoc test.