Research Paper Volume 9, Issue 7 pp 1698—1720

Aging and sarcopenia associate with specific interactions between gut microbes, serum biomarkers and host physiology in rats

Figure 7. Summary of host-microbial interactions in Aging and Sarcopenia. (A) Different aspects of host physiology impacted directly or indirectly by gut microbiome include nutrients, musculoskeletal and inflammation/immunity. (B) Illustration highlighting the shift within the microbial community in terms of members of Sutterella and Barnesiella with aging. Barnesiella is positively correlated to Clostridium XIVa and Papillibacter, which are all similarly correlated to aging phenotypes, specifically at the level of Lean Mass, Vitamin B12 levels, Lipid metabolism and Gastrocnemius muscle mass.