The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome
Figure 7.The cancer signaling pathway obtained from the Ingenuity Pathway Analysis
(IPA, www.qiagen.com/ingenuity) program. The normalized counts for each gene were correlated with the increase in calorie restriction (CR) level by Pearson correlation method. The pathway is colored based on a cut-off of an absolute correlation coefficient higher than 0.3. Red indicates a positive correlation with increasing CR level while green indicates a negative correlation. The string of Xs represent DNA and indicate a transcriptional effect of a gene.