Research Paper Volume 9, Issue 7 pp 1825—1843

Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13

Figure 4. CR reversed age induced upregulation of STAT3 protein expression. Representative western blotting and quantification of STAT3 protein expression in the livers of (A) 5 month old (open bars) or 24 months old (black bars) mice. (B) Mice on AL (open bars) or CR (black bars) mice. * - statistically significant difference (p<0.05). Western blot images displayed in the figure were not subjected to any manipulation.