Figure 6. TLR4 deficient mice are more efficient in IPGTT. (A) Time course of blood glucose concentration following intraperitoneal glucose load in old WT and in TLR4 deficient mice. The area under the curve (AUC) were calculated using the trapezoidal formula and plotted in the bar diagram (B). Data represented in bar diagrams are mean + SD of three independent experiments with WT and TLR4-KO mice (n=4). Significance of difference between means was determined by Student’s t-test and indicated **p<0.01.