Research Paper Volume 9, Issue 10 pp 2098—2116

A new mutation-independent approach to cancer therapy: Inhibiting oncogenic RAS and MYC, by targeting mitochondrial biogenesis

Figure 1. Experimental strategy for understanding MYC/RAS co-operativity in human breast CSCs. More specifically, we examined how MYC/RAS co-operation affects cellular metabolism and CSC propagation, allowing for the identification of a common metabolic therapy.