Research Paper Volume 9, Issue 11 pp 2302—2315

Selenium preserves keratinocyte stemness and delays senescence by maintaining epidermal adhesion

Figure 4. Keratinocyte relative adhesion to type IV collagen or laminin 332 during replicative senescence. Keratinocytes from 2 donors over subculture passages with or without SeNa supplementation and seeding at each passage on pre-coated wells with 10 µg/ml type IV collagen (on the left) or with 2 µg/ml laminin 332 (on the right). Results are the mean of n=3 measurements ± SD normalized to the mean of adhesion obtain from poly-D-lysine coated plates. *p<0.025, **p<0.005, ***p<0.0002.