Research Paper Volume 9, Issue 12 pp 2480—2488

Transfer of autologous mitochondria from adipose tissue-derived stem cells rescues oocyte quality and infertility in aged mice

Figure 2. Mitochondrial ultrastructure in adipocytes and ADSCs of aged mice. Mitochondrial with normal cristae and morphology in adipocytes (A) and ADSCs (B) of young mice (8-week-old). (C) In the adipocytes of aged mice (1-year-old), alternations in mitochondrial morphology was shown. Mitochiondria had abnormal swelling and different electron densities between inner and outer mitochondrial membranes. (D) Mitochondrial morphology in ADSCs of old mice appeared normal. Arrowheads indicate mitochondrial inner and outer membrane.