Editorial Volume 9, Issue 11 pp 2239—2240

Anti-telomerase T cells adoptive transfer

Figure 1. TERT-based adoptive cell therapy is an universal cancer immunotherapeutic approach. hTERT865-873-specific, TCR-engineered T-cells, as golden bullets, are able to selectively eliminate antigen positive (yellow spots) specific targets such as lymphoblastic and myeloid leukaemia cells and different solid tumor cells without affecting normal B and T lymphocytes as well as stem cells.