Research Paper Volume 9, Issue 12 pp 2587—2609

Mitogen-activated protein kinases, Fus3 and Kss1, regulate chronological lifespan in yeast

Figure 1. Subnetwork of yeast aging genes. A subnetwork was extracted from the yeast whole genome network, YeastNetv2, using the network analysis tool GeNA. The network topology was displayed using Cytoscape and shows the top 50 genes/proteins highly associated with documented age-affecting seed genes. Seed genes (Red); CLS increased (Green); CLS decreased (Blue). MAPKs FUS3, KSS1, and HOG1 are indicated by pink borders.