Research Paper Volume 9, Issue 12 pp 2610—2628

Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy

Figure 18. Comparison of the structures of (A) Diphenyleneiodonium (DPI), with the related compound (B) Diphenyliodonium chloride. Note the key similarities between these two chemical structures. Both of these classes of molecules target flavin-containing proteins.