Research Paper Volume 10, Issue 1 pp 83—99

Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

Figure 10. Effects of resveratrol in HK2 cells. Representative western blots of Nrf2, HO-1 and NQO-1 protein levels (A) and SIRT1, SOD1 and SOD2 protein levels (E). The Nrf2 was increased in the RSV group compared to H2O2 group (B). HO-1 as well as NQO-1 were significantly increased in the RSV group (C, D). Also, the expression of SIRT1 was significantly increased in the RSV group (F). Both SOD1 and SOD2 were higher in the RSV group than the H2O2 group (G, H). Quantitative analysis of the results is shown (*P<0.05, †P<0.001).