Research Paper Volume 10, Issue 1 pp 83—99

Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

Figure 9. Effects of resveratrol on renal oxidative stress. The 24-h urinary 8-epi-prostaglandin F2α (isoprostane) levels were decreased in the RSV group (A). Moreover, the 24-h concentration of urinary 8-hydroxy-deoxyguanosine was also decreased in the RSV group compared to that in the control (Cont) group (B). Significantly, the positive area expression of 8-OH-dG in renal tissue was decreased in the RSV group (C, D) (*P<0.05, †P<0.01, ‡P<0.0001).