Figure 1. Senescence of human BMECs. (A) Growth curves of P5 and P15 human BMECs, n=3, *P<0.05, compared to P5 on the same day. (B) Expression of senescence-associated marker p16INK4a in human BMECs, n=9. (C) Staining of young and senescent human BMECs for SA-β-Gal (left) and the percentage of β-gal positive cells (right), n=6. Data are presented as mean±SEM, *P<0.05, compared to P5.