Figure 1. Structure and function of LSD1 and LSD2. (A) Structure and domain organization of LSD1 and LSD2 proteins. Lysine 661 (K661) and lysine 666 (K666) are FAD binding sites for LSD1 and LSD2. Zf-CW, zinc finger CW domain. SWIRM, Swi3p, Rsc8p and Moira domain. (B) Factors that interact with LSD1 or LSD2.