Figure 2. Circulating pro-inflammatory chemokines were elevated in plasma of WT+BAPN mice. E-selectin, ICAM-1, P-selectin, IL-1β, IL-2, IL-6, TNF-α and MMP-9 were examined. IL-1β, IL-2, IL-6 and TNF-α and P-selectin were significantly higher in WT+BAPN mice. Values are mean ±SEM. *P<0.05 versus other groups, **P<0.01 versus other groups. MMP9 indicates matrix metalloproteinase 9; ICAM-1, intercellular cell adhesion molecule-1.