Research Paper Volume 10, Issue 3 pp 386—401

Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice

Figure 5. No effect of metformin on rapamycin-mediated mTORC1 inhibition. Quantification of phosphorylation/total protein ratios for S6 (left) and Akt (right) for liver, adipose tissue and muscle collected from male (A) and female (B) mice. Bars represent mean values for indicated diet/sex ± SEM. For all groups, n=6.