Editorial Volume 10, Issue 3 pp 301—302

Mitochondrial avatars for quantitative aging research

Figure 1. Quantitative responses compounded to produce the net effects of aging. The experimental simulation paradigm defined in this perspective describes a computational landscape that quantifies individual cellular responses (top panel), makes use of them in large multifaceted circuits to calculate net responses over time (middle panel), and ultimately determines the phenotypic viability outcomes for both mitochondrial and cell populations.