Research Paper Volume 10, Issue 5 pp 988—999

A novel functional polymorphism of GFAP decrease glioblastoma susceptibility through inhibiting the binding of miR-139

Figure 1. rs11558961 affected secondary structure of GFAP mRNA. In silico prediction of rs11558961 impact on RNA folding structures. The structures and Mountain plots for free energy or entropy corresponding to rs11558961C (A) or G allele (B). With G allele, there was an emerging miR-139 binding site exposed.