Research Paper Volume 10, Issue 5 pp 988—999

A novel functional polymorphism of GFAP decrease glioblastoma susceptibility through inhibiting the binding of miR-139

Figure 6. Schematic diagram for the potential functions of rs11558961 in GFAP expression and progression of GBM. rs11558961 variant G allele might decrease GFAP expression via forming a miR-139 binding site, and further suppress the metastasis and chemoresistance of GBM cells.