Research Paper Volume 10, Issue 6 pp 1257—1267

Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

Figure 2. Differential profiles of the gut microbiota between SAMR1 and SAMP8 mice. (A) Heat map of differential levels of bacteria between the groups. (B) Chao 1 index (t-test, P < 0.01). (C) Shannon index (t-test, P < 0.05). (D) Simpson index (t-test, P > 0.05). (E) PCoA analysis of gut bacteria data (Bray–Curtis dissimilarity). (F) PCA analysis of gut bacteria data. α-diversity data are shown as mean ± SEM (n = 10). PCA: principal component analysis; PCoA: principal coordinates analysis. *P < 0.05, **P < 0.01.