Research Paper Volume 10, Issue 6 pp 1366—1379

A panel of three oxidative stress-related genes predicts overall survival in ovarian cancer patients received platinum-based chemotherapy

Figure 5. GSEA delineates biological pathways associated with risk score in the validation group. Significantly enriched KEGG pathways (A) and BIOCARTA pathways (B) of the co-expressed genes with three oxidative stress-related genes. GSEA validated downregulated activity of (C) cell cycle, (D) IGF1/mTOR and (E) Fas pathways in low risk score group.