Research Paper Volume 10, Issue 6 pp 1380—1389

The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye

Figure 6. The effects of RPE/choroid eye-cup on BMDM complement gene expression. Naïve BMDMs were cultured in RPE/choroid eye cup from 18 months old mice for 7h. Macrophages were then isolated and processed for real-time RT-PCR analysis of complement genes. Mean ± SEM, n =3; *, P< 0.05; **, P < 0.01 compared to naïve BMDM alone, Unpaired Student t test.