Research Paper Volume 10, Issue 6 pp 1523—1533

Linc00472 suppresses proliferation and promotes apoptosis through elevating PDCD4 expression by sponging miR-196a in colorectal cancer

Figure 1. Linc00472 was decreased in CRC tissues and cells. (A) The expression levels of Linc00472 in CRC tumor tissues and adjacent normal tissues were determined by qRT-PCR assays. (B) Linc00472 expression was analyzed in TCGA colon adenocarcinoma (COAD) cohort. (C) qRT-PCR analysis was performed to detect Linc00472 expression in immortalized human colonic epithelial cell line NCM460 and four CRC cell lines (SW480, SW620, HT-29 and HCT-116). (D) Kaplan-Meier curve was employed to assess the overall survival outcome in CRC patients with high or low Linc00472 expression in TCGA dataset. *P < 0.05, ***P < 0.001.