Research Paper Volume 10, Issue 6 pp 1523—1533

Linc00472 suppresses proliferation and promotes apoptosis through elevating PDCD4 expression by sponging miR-196a in colorectal cancer

class="figure-viewer-img"

Figure 1. Linc00472 was decreased in CRC tissues and cells. (A) The expression levels of Linc00472 in CRC tumor tissues and adjacent normal tissues were determined by qRT-PCR assays. (B) Linc00472 expression was analyzed in TCGA colon adenocarcinoma (COAD) cohort. (C) qRT-PCR analysis was performed to detect Linc00472 expression in immortalized human colonic epithelial cell line NCM460 and four CRC cell lines (SW480, SW620, HT-29 and HCT-116). (D) Kaplan-Meier curve was employed to assess the overall survival outcome in CRC patients with high or low Linc00472 expression in TCGA dataset. *P < 0.05, ***P < 0.001.