Research Paper Volume 10, Issue 8 pp 1932—1946

Sirt6 deficiency impairs corneal epithelial wound healing

Figure 2. Corneal wound healing response in WT and Sirt6 KO mice. 2.0 mm central corneal epithelial debridement wounds were induced in 8-week-old WT and Sirt6 KO mice. (A) The corneas were photographed with fluorescein staining to visualize wounds before wounding or at various time points after wound injury. (B) The area of each epithelial defect was measured using ImageJ and the wound area was calculated as a percentage of the initial wound area. *p<0.05 compared with WT, n=6-12.