Figure 3. Effects of lycopene on decreased antioxidant status in D-gal-induced aged ovarian tissues and the activities of Nrf2/HO-1 pathway. (A) Effect of lycopene on decreased antioxidants status in the D-gal-induced aged ovarian tissues. (B) Effect of lycopene on the down-regulated expression of Nrf2, pNrf2 and HO-1, and the mRNA abundance of Nrf2 and HO-1. (C) Effect of lycopene on down-regulated mRNA abundance of Nrf2/HO-1 downstream genes. Values are expressed as the means±s.e.. Different lowercase letters indicate significant differences (P < 0.05).