Research Paper Volume 10, Issue 8 pp 2062—2078

LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer

Figure 4. CSE1L overexpression abrogated si-BANCR-mediated anti-invasion, anti-proliferation and pro-apoptosis effects in CRC cells. (A and B) The effect of BANCR overexpression on CSE1 L protein level was detected in LoVo and HCT116 cells. (C and D) The effect of BANCR knockdown on CSE1 L protein expression was measured in LoVo and HCT116 cells. (E-J) LoVo and HCT116 cells were transfected with si-Control, si-BANCR, si-BANCR+pcDNA-Control, si-BANCR+pcDNA-CSE1L, followed by the determination of cell viability (E and F), invasion capacity (G and H) and apoptosis rate (I and J). *P < 0.05.