Research Paper Volume 10, Issue 9 pp 2266—2283

Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of atherosclerosis in rabbits

Figure 8. The layout of dysregulated circRNA related ceRNA network (DCCN) and its structural characteristics. (A) The view of DCCN. The DCCN was comprised of 1452 edges between 365 mRNAs and 112 circRNAs. The blue nodes represented mRNA, the red nodes represented miRNAs, and the orange nodes represented circRNAs. (B) Degree distribution of DCCN. (C-D) Boxplot of degree and betweenness centrality of mRNAs and circRNAs.